When the Levee Breaks

Set in "Free to Be You and Me" season 5, after Sam decides to give up hunting, and finds out he is Lucifer's vessel. Instead of calling Dean he decides to take matters into his own hands. If there's no Sam, then Lucifer can't possess him, right? Sam tries to kill himself to avoid being possessed by Lucifer, but how are Dean and Cas going to feel about that?