(Story may contain Spoilers!) After Los Perdidos, the zombie parasite was cured with the help of Number 12, Nick Ramos, but the enemy has returned and the parasite has evolved and now all three heroes are back. This is the return of Frank West, Chuck Greene and Nick Ramos in their fight for survival...

The gods have decided to send their children to the death in a hunger games style way. Who will win and who will die?