Sam kills the demon and saves his friend, because demons don't always lie.
Sam runs into Jody and Alex on his junk food run for Dean at the end of "Soul Survivor," and they give him some much needed TLC.
After the funeral, Sam goes to the park where they met to mourn Jess.
Charlie braids Sam's hair.
While Charlie recovers from her ordeal in the bunker, Sam takes care of her and tells her about his experience with soullessness. Episode tag for s10e11, "There's No Place Like Home."
Sam adopts a dog since, as Jody keeps telling him, he's allowed to have nice things. Somehow, thanks in part to the large dog impressing on Dean the need for an attitude adjustment, this leads to a bunker occupied by two humans, four dogs, an ex-angel, and an ex-demon. And when Charlie, Dorothy, and a surprise guest return from Oz just in time for Christmas, the fun really begins.
Sam embraces his powers, but the way he uses them isn't exactly what the demons had in mind. AU for All Hell Breaks Loose Parts 1 and 2.
"Chicken or Beef?" AU where Luke tells Lorelai about what Dean said when he was drunk, and Lorelai goes to talk to Dean about it, forcing him to reconsider whether he's really ready to get married.
Dawn saves Jessica from Brady. After all the awkward explanations, it's clear that, whatever it is the Winchesters are dealing with, it's Slayer business.
Sam and Jess meet in a park when they're kids. Years later, friends at Stanford, they figure it out.
Sam goes with Jess to her family reunion, and receives help coping from an unlikely, adorable source.