Uncle Grandpa invites 20 lucky people to tour the UG RV, but it all takes a turn for the worst when everyone's favorite money-grubbing rat turns the friendly outing into a killing free-for all.

Sarah Nac, a major Uncle Grandpa fan, goes on a quest for some juicy information to update her website with. She finds something else instead... perhaps some love?

Uncle Grandpa gathers up 21 of his friends and puts them all in an Amusement Park he built in an effort to have them all get along with each other. Unfortunately for everyone, an evil rat named Tanezumi takes over the Amusement Park and turns the "getting along" premise into a survival game where they must kill each other in order to leave the Amusement Park.

New food is being served in all the town's restaurants and cafeterias, and the more people eat it the stranger they act! It's up to Uncle Grandpa, his RV crew, and some of the children he has significantly helped to solve the mysteries behind the strange new foods and save the city!