Cynthia is lost but where is she.

A day when Mr. Matthews has to take a sick day. Riley, Maya and Lucas end up ditching school for the day.

Becky has to take care of Jesse, while he is sick. Along with Michelle and Kelly who are sick as well. But, what happens when Jesse dreams about what would've happen if he never would've meet Becky.

The Flu has hit hard and the kids are all at risk of getting it. Tune in to find out what happens.

Charlotte walked out on Drew and now Drew is left to care for Angelica and even when times are tough, Angelica needs him the most of all. Between, taking Angelica to the doctors, caring for her when she is sick/hurt, taking her shopping for he first bra and boy trouble Drew doesn't know how he will deal with it alone.

Michelle comes down with the Chicken Pox on Christmas Eve.

Angelica goes to the doctors for a checkup and gets some unexpected news.

Matilda ends up having to miss school due to a sore throat. Ms. Honey stays home with her. Matilda may have to end up having her tonsils taken out.

The Rugrats experience their first day of preschool in different ways.