Kitamura Kami leads a completely normal life. But that all changes when a character from her favorite Anime, 'Katekyo Hitman Reborn', appears before her, therefore activating sort of a 'chain reaction' of characters to interrupt her otherwise quiet and peaceful living.
Tsuna and his guardians all have childhoods. This reveals the oddball phenomenon that intertwined their fates together, when they were innocent (well, some of them) little children.