Jane Rizzoli, former Homicide Detective works in the White House now for Edmond Isles, the president of the United States of America.

Detective Jane Rizzoli and Doctor Maura Isles get attacked in prison by nobody less then Charles Hoyt, Jane gets placed into a Victim Protection Program. Secret Services fake her death and Jane becomes Lindsay Boxer. She moves towards San Fran. to rebuild her life. When a though case comes along the SFPD team needs help from a certain Doctor. (Jane never killed Hoyt in this story.)