A chance encounter in the mission assignment office in Konoha, when Team's 7,8 and 10 were all there to receive their missions at the same time.

How would things have turned out in canon if, Uzukage had sent his oldest daughter, along with several of his children to a distant but prosperous island to establish a branch of the clan. Seeking merely profit, the expedition allowed the clan to survive. This will derail canon quite a bit.