Vergil has been poisoned and it's up to a human woman to heal him. Through the journey, the two end up learning about themselves and each other. (Post DMC5. Vergil/OC. I want to dig into Vergil's character now that his mind has been cleared of the nightmares and he's more accepting of his humanity. Just for fun.)
Ripley's past haunts her so she lives in the present with no direction. Dangerous men are after her, and with the help of a certain vigilante, she's fighting to stay away from the person she used to be. Vaguely follows game continuity. Aiden/OC