Owen & Amelia each seek a person and they bond as friends. Over time, their connection grows. Their growing closeness causes the lines to blur between being friends, friends with benefits, or something more. The couple marries and faces surprising realities as they begin a family and live with the unpredictable. This is the first story in a series.

This series follows Jo Wilson and Alex Karev as they navigate life-changing decisions and their evolving relationship. Some chapters describe more day-to-day matters, while others explore larger topics.

Alex and Jo were recently married and were beginning to settle into a routine as husband and wife. One day, Jo answers the phone and hears the voice of Alex's sister, Amber, on the other line. In an instant, everything is drastically different. Suddenly, they go from being carefree newlyweds to acquiring new roles that challenge and change their lives.

Originally posted as a stand-alone (but later added as Chapter 3 in The Circuitous Route), this entry shows how Alex has his hands full as life sends him spinning with considerations. What will become of Yang's board seat and the shares to the hospital? How should Alex handle situations with his ex- and future wives? And perhaps most importantly, what's the best pet name for Jo?

Originally posted as a stand alone, this became Chapter 2 of The Circuitous Route. In this entry, Jo's life as a resident includes peculiar requests from Derek, Alex and Meredith as the attendings attempt to navigate their busy lives. As he has done before, Alex shocks Jo with an invitation to join him in an unexpected way.