Almost two years after the events of 'Voracity', Hannibal Lecter has started a new life in Italy, carefully carving his way into its high society. When an unexpected visitor disrupts his plans, he chases the chaos back to America as a new serial killer emerges with a singular vendetta. Can the FBI convince Will Graham to help them hunt down the latest threat?

A restless nineteen year old finds herself caught in a whirlwind of pretty lies, ugly truths and disturbing crimes when she decides to cure her boredom by posing as a patient in a psychiatric hospital in an attempt to find out why her grandfather died there long before she was born. Consequently, a killer (or two) take a liking to her. Perhaps ignorance really is bliss. Hannibal&OC