Three years after the event of the I-Cubit scam that shook the world, the colorful and creative Mixels have drifted apart. With the help of a terrifying new power, King Nixel scatters the Mixels to the winds and takes over Mixopolis once more. Hope is not lost, and a new, monochrome Mixel sets out to discover his past, stop the Nixel Armada, and unite all Mixels!