[Years after both series ended] The Boiling Isle civilians discover that they were sealed away from the rest of the Netherworld until now. Luz must endure the Collector's curse following their defeat. Demons are disappearing on the Boiling Isles. Amity struggles with a question. A teenage King, void of ambitions, finds himself connected... to Iruma and Ameri's unborn child.

Ines Coeurdor is a uniquely good girl. However, when her father was supposed to tell her a secret on her sixteenth birthday, she gets murdered. Reborn in Hell as Indigo Caligo, an owl butterfly demon, she deals with panicked anxieties as she finds shelter in the Hazbin Hotel, where she meets demons acting as second family while she tries to understand why she's in Hell with no sin.

Set after the events of DESCENDANTS 3. After weeks of self-loathing, Audrey runs away to help Gothy Gothel find her missing sibling. An adventure consisting of traps, trips to different worlds and inhuman creatures that eventually lead Audrey to face the worst dangers in her life: dark forces after her life and the devil on her shoulder who still calls her his Queen of Mean.